Communicating transaction-specific attributes in a peripheral component interconnect express (PCIe) system is disclosed. A PCIe system includes a host system and at least one PCIe endpoint. The PCIe endpoint is configured to determine one or more transaction-specific attributes that can improve efficiency and performance of a predefined host transaction. In this regard, in one aspect, the PCIe endpoint encodes the transaction-specific attributes in a transaction layer packet (TLP) prefix of at least one PCIe TLP and provides the PCIe TLP to the host system. In another aspect, a PCIe root complex (RC) in the host system is configured to detect and extract the transaction-specific attributes from the TLP prefix of the PCIe TLP received from the PCIe endpoint. By communicating the transaction-specific attributes in the TLP prefix of the PCIe TLP, it is possible to improve efficiency and performance of the PCIe system without violating the existing PCIe standard.