Invention Grant
- Patent Title: Library of pH responsive polymers and nanoprobes thereof
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Application No.: US15369701Application Date: 2016-12-05
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Publication No.: US10098971B2Publication Date: 2018-10-16
- Inventor: Jinming Gao , Gang Huang , Tian Zhao , Xinpeng Ma , Yiguang Wang , Yang Li , Baran D. Sumer
- Applicant: The Board of Regents of the University of Texas System
- Applicant Address: US TX Austin
- Assignee: The Board of Regents of the University of Texas System
- Current Assignee: The Board of Regents of the University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- Main IPC: A61K49/00
- IPC: A61K49/00 ; G01N33/84 ; G01N33/58 ; C08F8/30 ; C08F8/42 ; C08F8/32 ; C08F8/34 ; C09B69/10 ; G01N21/64

Abstract:
The present disclosure relates to polymers which contain a hydrophobic and hydrophilic segment which is sensitive to pH. In some aspects, the polymers form a micelle which is sensitive to pH and results in a change in fluorescence based upon the particular pH. In some aspects, the disclosure also provides methods of using the polymers for the imaging of cellular or extracellular environment or delivering a drug.
Public/Granted literature
- US20170143852A1 LIBRARY OF PH RESPONSIVE POLYMERS AND NANOPROBES THEREOF Public/Granted day:2017-05-25
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