A method may include, in an apparatus comprising a closed loop amplifier and a signal processing block configured to generate an amplifier input signal as a function of an upstream signal received at an input of the signal processing block, in a calibration mode of the apparatus: decoupling a second stage input of the amplifier from a first stage output of the amplifier; determining an offset signal that when applied to the input of a signal processing block as the upstream signal generates approximately zero as an intermediate signal generated by the first stage of the amplifier; and controlling one or more parameters of the apparatus based on the offset signal to compensate for an offset of at least one of the first stage and the signal processing block.