Invention Grant
- Patent Title: Methods for treating Filoviridae virus infections
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Application No.: US15902690Application Date: 2018-02-22
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Publication No.: US10251898B2Publication Date: 2019-04-09
- Inventor: Byoung Kwon Chun , Michael O'Neil Hanrahan Clarke , Edward Doerffler , Hon Chung Hui , Robert Jordan , Richard L. Mackman , Jay P. Parrish , Adrian S. Ray , Dustin Siegel
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: GILEAD SCIENCES, INC.
- Current Assignee: GILEAD SCIENCES, INC.
- Current Assignee Address: US CA Foster City
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Main IPC: A61K31/706
- IPC: A61K31/706 ; A61K31/7056 ; A61K31/685 ; C07D487/04 ; C07D519/00 ; C07F9/24 ; C07F9/6561 ; A61K31/675 ; A61K45/06 ; A61K31/00 ; A61K31/53 ; C07H1/00 ; C07H1/02 ; C07H11/00 ; C07H15/18 ; A61K31/6615 ; A61K31/665 ; A61K31/683
Abstract:
Provided are compounds, methods, and pharmaceutical compositions for treating Filoviridae virus infections by administering ribosides, riboside phosphates and prodrugs thereof, of Formula IV: The compounds, compositions, and methods provided are particularly useful for the treatment of Marburg virus, Ebola virus and Cueva virus infections.
Public/Granted literature
- US20180311263A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS Public/Granted day:2018-11-01
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