Invention Grant
- Patent Title: GDF15 fusion proteins and uses thereof
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Application No.: US15586463Application Date: 2017-05-04
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Publication No.: US10336812B2Publication Date: 2019-07-02
- Inventor: Anthony Armstrong , Judith Ann Connor , Jennifer Furman , Chichi Huang , Michael J. Hunter , Xiefan Lin-Schmidt , Serena Nelson , Shamina Rangwala , Shannon Mullican , Jose Antonio Chavez
- Applicant: Janssen Biotech, Inc.
- Applicant Address: US PA Horsham
- Assignee: Janssen Biotech, Inc.
- Current Assignee: Janssen Biotech, Inc.
- Current Assignee Address: US PA Horsham
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/16 ; A61K38/17 ; A61K38/18 ; A61K38/19 ; C07K14/00 ; C07K14/435 ; C07K14/46 ; C07K14/47 ; C07K14/475 ; C07K14/51 ; C07K14/765 ; C12N1/11 ; C12N1/13 ; C12N1/15 ; C12N1/21 ; C12N5/10 ; C12N15/00 ; C12N15/09 ; C12N15/11 ; C12N15/12 ; C12N15/14 ; C12N15/62 ; C12N15/63 ; C12N5/12
Abstract:
Fusion proteins containing a half-life extension protein, a linker, and a GDF15 protein are described. Also described are nucleic acids encoding the fusion proteins, recombinant cells thereof, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing metabolic diseases, disorders or conditions.
Public/Granted literature
- US20170327560A1 GDF15 FUSION PROTEINS AND USES THEREOF Public/Granted day:2017-11-16
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