Invention Grant
- Patent Title: Fused tricyclic pyrazole derivatives useful for farnesoid X receptors
-
Application No.: US15569498Application Date: 2016-04-29
-
Publication No.: US10351576B2Publication Date: 2019-07-16
- Inventor: Donatella Chianelli , Xiaodong Liu , Valentina Molteni , John Nelson , Jason Roland , Paul Vincent Rucker , David Charles Tully
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Genomics Institute of the Novartis Research Foundation
- Agent Emily T. Wu
- International Application: PCT/IB2016/052424 WO 20160429
- International Announcement: WO2016/174616 WO 20161103
- Main IPC: C07D491/052
- IPC: C07D491/052 ; C07D493/04 ; A61K31/4162 ; A61K31/427 ; A61K31/5377 ; A61K31/635
Abstract:
The present invention relates to compounds of Formula I, a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X receptors (FXR).
Public/Granted literature
- US20180298018A1 FUSED TRICYCLIC PYRAZOLE DERIVATIVES USEFUL FOR FARNESOID X RECEPTORS Public/Granted day:2018-10-18
Information query
