Invention Grant
- Patent Title: Process and intermediates for the preparation of NEP inhibitors
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Application No.: US15550224Application Date: 2016-02-11
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Publication No.: US10385004B2Publication Date: 2019-08-20
- Inventor: Benjamin Martin , Francesca Mandrelli , Francesco Venturoni
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Judith D. Kuntz
- Priority: EP15155147 20150213
- International Application: PCT/IB2016/050725 WO 20160211
- International Announcement: WO2016/128924 WO 20160818
- Main IPC: C07C201/10
- IPC: C07C201/10 ; C07C201/12 ; C07C227/04 ; C07C335/16 ; C07F9/535 ; C07D207/06 ; B01J31/02 ; C07C205/04 ; C07C205/44 ; C07C205/51 ; C07F7/18

Abstract:
The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril. It further relates to new intermediate compounds and their use for said new chemical synthesis route.
Public/Granted literature
- US20180022690A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF NEP INHIBITORS Public/Granted day:2018-01-25
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