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公开(公告)号：US20160263566A1
公开(公告)日：2016-09-15
申请号：US15164002
申请日：2016-05-25
Applicant: AbbVie Inc.
Inventor： Shashank Shekhar , Thaddeus S. Franczyk , David M. Barnes , Travis B. Dunn , Anthony R. Haight , Vincent S. Chan
IPC: B01J31/24 , C07F9/6571 , C07C17/263 , C07C41/30 , C07F9/48 , C07F9/6558 , C07F9/6503 , C07F9/572 , C07F9/50 , C07C303/40 , C07D209/42 , C07D213/76 , C07D239/54 , C07C41/01 , C07C273/18 , C07C253/30 , C07C201/10 , C07D209/34 , C07C1/26 , C07F5/04 , C07C17/361 , C07D295/033 , C07C319/14 , C07C45/61 , C07F9/40 , C07F9/6568
CPC classification number: B01J31/2423 , B01J31/189 , B01J31/2419 , B01J31/2438 , B01J31/2466 , B01J31/2485 , B01J31/249 , B01J2231/4211 , B01J2231/4227 , B01J2231/4277 , B01J2231/4283 , B01J2231/4288 , B01J2231/4294 , B01J2231/44 , B01J2531/0205 , B01J2531/0266 , B01J2531/0288 , B01J2531/824 , B01J2540/10 , B01J2540/40 , C07C1/26 , C07C1/30 , C07C1/321 , C07C17/093 , C07C17/2635 , C07C17/361 , C07C41/01 , C07C41/30 , C07C45/61 , C07C45/68 , C07C45/71 , C07C201/10 , C07C253/14 , C07C253/30 , C07C273/1854 , C07C273/1863 , C07C303/36 , C07C303/40 , C07C319/14 , C07C2531/24 , C07C2531/26 , C07D209/12 , C07D209/34 , C07D209/42 , C07D213/76 , C07D239/54 , C07D265/30 , C07D295/033 , C07F1/02 , C07F5/025 , C07F5/04 , C07F9/4021 , C07F9/4841 , C07F9/505 , C07F9/5072 , C07F9/509 , C07F9/572 , C07F9/65031 , C07F9/65583 , C07F9/65683 , C07F9/657163 , Y02P20/52 , C07C275/28 , C07C311/08 , C07C311/21 , C07C311/29 , C07C255/10 , C07C321/30 , C07C205/45 , C07C15/06 , C07C49/784
Abstract: The disclosure is directed to: (a) phosphacycle ligands; (b) catalyst compositions comprising phosphacycle ligands; and (c) methods of using such phosphacycle ligands and catalyst compositions in bond forming reactions.
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公开(公告)号：US08865930B2
公开(公告)日：2014-10-21
申请号：US12737739
申请日：2009-08-10
Applicant: Joseph P. Noel , Justin Ramsey , Thomas J. Baiga
Inventor： Joseph P. Noel , Justin Ramsey , Thomas J. Baiga
IPC: C07C69/74 , C07C69/013 , C07C67/00 , C07C69/608 , C07C69/78 , C07C201/10 , C07C205/03 , C07C315/04
CPC classification number: C07C69/013 , C07C67/00 , C07C69/608 , C07C69/78 , C07C201/10 , C07C205/03 , C07C315/04 , C07C2602/28 , C07C317/14 , C07C317/28
Abstract: Disclosed herein is a method for synthesizing terpenoid compounds, as well as compositions comprising terpenoids and methods for their use. In one aspect the process is represented by the scheme wherein G is X is and R1, R2 and R3 independently are selected from H, acyl, lower alkyl and aralkyl; and Y is —O—, —S— or —NH—, and R4 is selected from H, acyl, lower alkyl and aralkyl.
Abstract translation: 本文公开了一种合成萜类化合物的方法，以及包含萜类化合物的组合物及其用途。 在一个方面，该方法由其中G是X是且R 1，R 2和R 3独立地选自H，酰基，低级烷基和芳烷基的方案表示。 并且Y是-O - ， - S-或-NH-，并且R 4选自H，酰基，低级烷基和芳烷基。
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公开(公告)号：US20140179936A1
公开(公告)日：2014-06-26
申请号：US14054063
申请日：2013-10-15
Applicant: AEL MINING SERVICES LIMITED
Inventor： Andre Pienaar , Laurence Justin Pienaar Wilson , Michael Stockenhuber
IPC: C06B49/00 , C07D301/12 , C07C201/10 , C07C273/18
CPC classification number: C06B49/00 , C07C29/36 , C07C201/02 , C07C201/10 , C07C273/18 , C07C273/1809 , C07C273/1863 , C07D301/12 , C07C31/24 , C07C275/50 , C07C275/06 , C07C203/04
Abstract: A method producing a surfactant from glycerol by converting glycerol, in a first step, to glycidol, polymerizing glycidol to an aliphatic alcohol and finally substituting a hydroxyl group with a substitute anion.
Abstract translation: 通过将甘油转化成缩水甘油，将缩水甘油聚合成脂肪族醇，最后用取代阴离子取代羟基，从甘油中转化甘油的方法。
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公开(公告)号：US20140066662A1
公开(公告)日：2014-03-06
申请号：US14012411
申请日：2013-08-28
Applicant: BROMINE COMPOUNDS LTD.
Inventor： Jacob OREN
IPC: C07C201/10
CPC classification number: C07C201/10 , C07C201/12 , C07C205/15
Abstract: The invention provides a process for preparing bronopol, which process comprises charging a reaction vessel with water, bromopicrin, nitromethane and paraformaldehyde, gradually feeding a base into said reaction vessel under stirring, bringing the reaction to completion and separating bronopol from the aqueous reaction mixture.
Abstract translation: 本发明提供了一种制备青霉酚的方法，该方法包括向反应容器中加入水，溴氰菊酯，硝基甲烷和多聚甲醛，在搅拌下逐渐向碱性物质中加入碱，使反应完成，并从反应混合物中分离出丙三醇。
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公开(公告)号：US20100324139A1
公开(公告)日：2010-12-23
申请号：US12810244
申请日：2008-12-19
Applicant: Abhay Gaitonde , Debashish Datta , Bindu Manojkumar , Sunanda Phadtare
Inventor： Abhay Gaitonde , Debashish Datta , Bindu Manojkumar , Sunanda Phadtare
IPC: C07C227/04 , C07C201/10 , C07C227/34 , C07C69/716 , C07C69/675 , C07C69/63 , C07C229/08 , A61K31/197 , A61P29/00 , A61P9/10 , A61P25/24 , A61P25/22 , A61P25/08 , A61P25/18
CPC classification number: C07C227/32 , C07B2200/07 , C07C67/307 , C07C67/31 , C07C67/343 , C07C201/12 , C07C227/04 , C07C229/08 , C07C309/65 , C12P7/42 , C12P41/002 , C07C69/63 , C07C69/675 , C07C69/716 , C07C205/51
Abstract: The present invention relates to a novel method for the preparation of racemic pregabalin (1) or a single enantiomer thereof, (S)-(+)-3-(aminomethyl)-5-methyl-hexanoic acid (2).
Abstract translation: 本发明涉及一种制备外消旋普瑞巴林（1）或其单一对映异构体（S） - （+） - 3-（氨基甲基）-5-甲基 - 己酸（2）的新方法。
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Patent Agency Ranking
公开(公告)号：US5998661A
公开(公告)日：1999-12-07
申请号：US100782
申请日：1998-06-15
Applicant: Abdollah Bashir-Hashemi
Inventor： Abdollah Bashir-Hashemi
IPC: C07C201/10 , C07C205/05 , C07C205/57 , C07C205/00 , C07C61/08
CPC classification number: C07C201/10 , C07C2103/74 , C07C2103/90
Abstract: A process for selective, direct oxidation of amine or amine hydrochloride mpounds is described. It uses mixed oxidizing agents of monopersulfate and ozone.
Abstract translation: 描述了胺或胺盐酸盐化合物的选择性，直接氧化的方法。 它使用单过硫酸盐和臭氧的混合氧化剂。
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公开(公告)号：US3968130A
公开(公告)日：1976-07-06
申请号：US300689
申请日：1972-10-25
Applicant: Istvan Szekely
Inventor： Istvan Szekely
IPC: C07C67/00 , C07C201/00 , C07C201/10 , C07C205/47 , C07C79/37
CPC classification number: C07C205/47 , C07C201/08 , C07C2103/24
Abstract: The invention relates to a process for the manufacture of anthraquinones which are mononitrated in the .alpha.-position, especially 1-nitroanthraquinone, wherein an anthraquinone which possesses at least 1 free .alpha.-position and is optionally substituted in the other .alpha.-position with halogen, preferably chlorine, or with hydroxyl groups, but especially the unsubstituted anthraquinone, is nitrated with concentrated nitric acid without further additives adiabatically, or at temperature above 40.degree.C isothermically, and optionally under pressure.
Abstract translation: 本发明涉及一种制备在α-位上单硝化的蒽醌的方法，特别是1-硝基蒽醌，其中具有至少1个游离α-位且在另一个α-位上被卤素任选取代的蒽醌， 优选氯，或羟基，但特别是未取代的蒽醌，用浓硝酸进行硝酸化，无另外的添加剂绝热，或在40℃以上的温度等温和任选在压力下进行硝化。
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公开(公告)号：US2780657A
公开(公告)日：1957-02-05
申请号：US40214254
申请日：1954-01-04
Applicant: CALIFORNIA RESEARCH CORP
Inventor： TOLAND JR WILLIAM G
IPC: C07C201/10 , C07C205/06
CPC classification number: C07C201/10 , C07C205/06
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公开(公告)号：US20180022690A1
公开(公告)日：2018-01-25
申请号：US15550224
申请日：2016-02-11
Applicant: Novartis AG
Inventor： Benjamin MARTIN , Francesca MANDRELLI , Francesco VENTURONI
IPC: C07C201/10 , C07C205/44 , C07C205/04 , B01J31/02 , C07C335/16 , C07D207/06 , C07F9/535 , C07C205/51 , C07C201/12
CPC classification number: C07C201/10 , B01J31/0237 , B01J31/0241 , B01J31/0244 , B01J31/0265 , C07B2200/07 , C07C201/12 , C07C205/04 , C07C205/44 , C07C205/51 , C07C227/04 , C07C335/16 , C07C2601/14 , C07C2602/08 , C07D207/06 , C07F7/1804 , C07F9/5355 , C07C205/53 , C07C229/34
Abstract: The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril. It further relates to new intermediate compounds and their use for said new chemical synthesis route.
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公开(公告)号：US09669399B2
公开(公告)日：2017-06-06
申请号：US15164002
申请日：2016-05-25
Applicant: AbbVie Inc.
Inventor： Shashank Shekhar , Thaddeus S. Franczyk , David M. Barnes , Travis B. Dunn , Anthony R. Haight , Vincent S. Chan
IPC: C07F9/6568 , C07C303/40 , B01J31/24 , C07D209/12 , C07D213/76 , C07D239/54 , C07C253/30 , C07C201/10 , C07D209/34 , C07D265/30 , C07C1/30 , C07C17/093 , C07C41/01 , C07C45/71 , C07C253/14 , C07C273/18 , C07C303/36 , C07C319/14 , C07D209/42 , C07D295/033 , C07F5/02 , C07F9/40 , C07C1/32 , C07C45/68 , C07F1/02 , C07F9/50 , C07C1/26 , C07C17/263 , C07C17/361 , C07C41/30 , C07C45/61 , C07F5/04 , C07F9/48 , C07F9/572 , C07F9/6503 , C07F9/6558 , C07F9/6571 , B01J31/18
CPC classification number: B01J31/2423 , B01J31/189 , B01J31/2419 , B01J31/2438 , B01J31/2466 , B01J31/2485 , B01J31/249 , B01J2231/4211 , B01J2231/4227 , B01J2231/4277 , B01J2231/4283 , B01J2231/4288 , B01J2231/4294 , B01J2231/44 , B01J2531/0205 , B01J2531/0266 , B01J2531/0288 , B01J2531/824 , B01J2540/10 , B01J2540/40 , C07C1/26 , C07C1/30 , C07C1/321 , C07C17/093 , C07C17/2635 , C07C17/361 , C07C41/01 , C07C41/30 , C07C45/61 , C07C45/68 , C07C45/71 , C07C201/10 , C07C253/14 , C07C253/30 , C07C273/1854 , C07C273/1863 , C07C303/36 , C07C303/40 , C07C319/14 , C07C2531/24 , C07C2531/26 , C07D209/12 , C07D209/34 , C07D209/42 , C07D213/76 , C07D239/54 , C07D265/30 , C07D295/033 , C07F1/02 , C07F5/025 , C07F5/04 , C07F9/4021 , C07F9/4841 , C07F9/505 , C07F9/5072 , C07F9/509 , C07F9/572 , C07F9/65031 , C07F9/65583 , C07F9/65683 , C07F9/657163 , Y02P20/52 , C07C275/28 , C07C311/08 , C07C311/21 , C07C311/29 , C07C255/10 , C07C321/30 , C07C205/45 , C07C15/06 , C07C49/784
Abstract: The disclosure is directed to: (a) phosphacycle ligands; (b) catalyst compositions comprising phosphacycle ligands; and (c) methods of using such phosphacycle ligands and catalyst compositions in bond forming reactions.
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