Systems and methods for determining quantization parameter (QP) for video coding. Embodiments may be particularly advantageous for strongly temporal correlated frames, such as for video conferencing applications. An initial QP for a frame of a video sequence may be modified based on a spatial complexity or a temporal complexity associated with the video frame, and/or based on an inter-predicted frame bitrate target cycle, as a function of whether the frame is intra- or inter-predicted. The inter-predicted frame bitrate target cycle includes a sequence of two or more inter-predicted frame bitrate targets that are assigned to the frame according to the inter-predicted frame bitrate target cycle. A reference frame for an inter-predicted frame may be selected based on the bitrate target associated with candidate reference frames. Initial QP of an inter-predicted frame with a scene change may be modified in a manner independent of an inter-predicted frame bitrate target cycle.