Invention Grant
- Patent Title: DNA sequencing by synthesis using modified nucleotides and nanopore detection
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Application No.: US13994431Application Date: 2011-12-16
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Publication No.: US10443096B2Publication Date: 2019-10-15
- Inventor: Jingyue Ju , Shiv Kumar , Zengmin Li , Chuanjuan Tao , Minchen Chien , James J. Russo , Sergey Kalachikov , Ken Shepard , Jacob Karl Rosenstein
- Applicant: Jingyue Ju , Shiv Kumar , Zengmin Li , Chuanjuan Tao , Minchen Chien , James J. Russo , Sergey Kalachikov , Ken Shepard , Jacob Karl Rosenstein
- Applicant Address: US NY New York
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee Address: US NY New York
- Agency: Cooper & Dunham LLP
- Agent John P. White; Gary J. Gershik
- International Application: PCT/US2011/065640 WO 20111216
- International Announcement: WO2012/083249 WO 20120621
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6869 ; C07H19/10 ; C07H21/00 ; G01N33/487

Abstract:
This disclosure is related to a method of sequencing a single-stranded DNA using deoxynucleotide polyphosphate analogues and translocation of tags from incorporated deoxynucleotide polyphosphate analogues through a nanopore.
Public/Granted literature
- US20130264207A1 DNA SEQUENCING BY SYNTHESIS USING MODIFIED NUCLEOTIDES AND NANOPORE DETECTION Public/Granted day:2013-10-10
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