- 专利标题： Engineered beta-subunit of tryptophan synthase for production of non-canonical amino acids
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申请号： US15094458申请日： 2016-04-08
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公开(公告)号： US10513719B2公开(公告)日： 2019-12-24
- 发明人: Andrew Richard Buller , Sabine Brinkmann-Chen , Michael Herger , David K. Romney , Javier Murciano Calles , Paul van Roye
- 申请人： The California Institute of Technology
- 申请人地址： US CA Pasadena
- 专利权人： THE CALIFORNIA INSTITUTE OF TECHNOLOGY
- 当前专利权人： THE CALIFORNIA INSTITUTE OF TECHNOLOGY
- 当前专利权人地址： US CA Pasadena
- 代理机构： Kilpatrick Townsend & Stockton LLP
- 主分类号： C12N9/88
- IPC分类号： C12N9/88 ; C12N1/21 ; C12N15/60 ; C12P13/22 ; C12P13/04
摘要：
This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells expressing such modified subunits and methods of producing non-canonical amino acids.
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