Systems, apparatus, and methods to deploy safety equipment from a drone are disclosed. An example apparatus includes a sensor to gather environmental data and an analyzer in communication with the sensor. In this example, the analyzer is to identify an anchor site based on the environmental data and produce an assessment of stability of the anchor site based on the environmental data and model data. The example apparatus also includes one or more actuators to deploy a securing device in response to the assessment of the analyzer indicating the anchor site is stable and to deploy the safety equipment.