- 专利标题： Anti-factor D antibody variant conjugates and uses thereof
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申请号： US15336522申请日： 2016-10-27
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公开(公告)号： US10654932B2公开(公告)日： 2020-05-19
- 发明人: Philip E. Hass , Robert F. Kelley , Justin M. Scheer , Whitney Shatz , Devin Tesar , Menno van Lookeren Campagne
- 申请人： Genentech, Inc.
- 申请人地址： US CA South San Francisco
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Armstrong Teasdale LLP
- 主分类号： A61K45/06
- IPC分类号： A61K45/06 ; A61K9/00 ; A61K47/60 ; C07K16/18 ; C07K16/22 ; C07K16/28 ; A61K39/00
摘要：
The disclosure relates to antibody-polymer conjugates comprising one or more anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.