-
公开(公告)号：US20130149308A1
公开(公告)日：2013-06-13
申请号：US13763896
申请日：2013-02-11
申请人： Genentech, Inc.
IPC分类号： C07K16/24
CPC分类号： C07K16/244 , A61K2039/507 , C07K16/245 , C07K2317/76
摘要： The present invention relates to compositions and methods for treatment of disease. More particularly, the present invention relates to anti-IL-1β and anti-IL-18 antibodies, including anti-IL-1β and anti-IL-18 bispecific antibodies, and methods of treating disease using such antibodies.
摘要翻译： 本发明涉及治疗疾病的组合物和方法。 更具体地，本发明涉及抗IL-1β和抗IL-18抗体，包括抗IL-1β和抗IL-18双特异性抗体，以及使用这种抗体治疗疾病的方法。
-
公开(公告)号：US10654932B2
公开(公告)日：2020-05-19
申请号：US15336522
申请日：2016-10-27
申请人： Genentech, Inc.
发明人： Philip E. Hass , Robert F. Kelley , Justin M. Scheer , Whitney Shatz , Devin Tesar , Menno van Lookeren Campagne
摘要： The disclosure relates to antibody-polymer conjugates comprising one or more anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
-
公开(公告)号：US10179821B2
公开(公告)日：2019-01-15
申请号：US14700853
申请日：2015-04-30
申请人： Genentech, Inc.
IPC分类号： A61K39/395 , C07K16/40 , A61K9/00 , A61K39/00
摘要： The invention relates to anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
-
公开(公告)号：US20170143843A1
公开(公告)日：2017-05-25
申请号：US15336522
申请日：2016-10-27
申请人： Genentech, Inc.
发明人： Philip E. Hass , Robert F. Kelley , Justin M. Scheer , Whitney Shatz , Devin Tesar , Menno van Lookeren Campagne
CPC分类号： C07K16/2863 , A61K9/0048 , A61K45/06 , A61K47/60 , A61K2039/505 , C07K16/18 , C07K16/22 , C07K2317/55 , C07K2317/92 , C07K2317/94
摘要： The disclosure relates to antibody-polymer conjugates comprising one or more anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
-
公开(公告)号：US20190016826A1
公开(公告)日：2019-01-17
申请号：US16143098
申请日：2018-09-26
申请人： Genentech, Inc.
发明人： Yan Wu , Menno van Lookeren Campagne , Daniel Kirchhofer , Michael Terry Lipari , Kenneth J. Katschke, JR. , Paul M. Moran , Scott Stawicki , Wei-Ching Liang
IPC分类号： C07K16/40
摘要： The invention provides anti-HtrA1 antibodies and methods of using the same.
-
公开(公告)号：US10961313B2
公开(公告)日：2021-03-30
申请号：US16730018
申请日：2019-12-30
申请人： Genentech, Inc.
发明人： Philip E. Hass , Robert F. Kelley , Justin M. Scheer , Whitney Shatz , Devin Tesar , Menno van Lookeren Campagne
摘要： The disclosure relates to antibody-polymer conjugates comprising one or more anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
-
公开(公告)号：US20160017052A1
公开(公告)日：2016-01-21
申请号：US14700853
申请日：2015-04-30
申请人： GENENTECH, INC.
发明人： Robert F. Kelley , Menno van Lookeren Campagne , Justin M. Scheer , Philip E. Hass , Devin Tesar
IPC分类号： C07K16/40 , A61K9/00 , A61K39/395
CPC分类号： C07K16/40 , A61K9/0048 , A61K2039/505 , C07K2317/55 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： The invention relates to anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
摘要翻译： 本发明涉及抗因子D抗体变体，其生产及其在制备用于治疗与过量或不受控补体活化相关的疾病和病症的组合物和药物中的用途。
-
-
-
-
-
-
搜索结果
7 条记录 (耗时 0.021 秒)