Invention Grant
- Patent Title: Ultrapurified DsbA and DsbC and methods of making and using the same
-
Application No.: US16044360Application Date: 2018-07-24
-
Publication No.: US10690671B2Publication Date: 2020-06-23
- Inventor: Marc Wong , Liliana T. Yee , Amy Lim , Chris B. Fong
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Morrison & Foerster LLP
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/573 ; C12N9/02 ; C12N9/90 ; C07K1/22 ; C07K16/40 ; A61K38/00
Abstract:
The present invention provides methods for producing disulfide oxidoreductase A (DsbA) and disulfide oxidoreductase C (DsbC) polypeptides at very high levels of purity. Also provided are ultrapure DsbA and DsbC and methods of using same, e.g., for use in immunoassays to show removal of DsbA and DsbC from biologics produced in bacteria.
Public/Granted literature
- US20190056399A1 ULTRAPURIFIED DsbA AND DsbC AND METHODS OF MAKING AND USING THE SAME Public/Granted day:2019-02-21
Information query
IPC分类:
