Invention Grant
- Patent Title: Separation matrix
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Application No.: US16682855Application Date: 2019-11-13
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Publication No.: US10711035B2Publication Date: 2020-07-14
- Inventor: Gustav José Rodrigo , Tomas Bjorkman , Mats Ander , Jesper Ulf Hansson
- Applicant: GE HEALTHCARE BIOPROCESS R&D AB
- Applicant Address: SE Uppsala
- Assignee: GE HEALTHCARE BIOPROCESS R&D AB
- Current Assignee: GE HEALTHCARE BIOPROCESS R&D AB
- Current Assignee Address: SE Uppsala
- Agency: Eversheds Sutherland (US) LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@5e3d700f com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@43b17c55
- Main IPC: A23J1/00
- IPC: A23J1/00 ; C07K1/22 ; C07K16/00 ; C07K14/31 ; B01J20/28 ; B01J20/24 ; B01J20/32 ; B01D15/38 ; C07K17/10 ; B01J20/286 ; C07K16/06

Abstract:
The invention relates to a separation matrix comprising at least 11 mg/ml Fc-binding ligands covalently coupled to a porous support, wherein: a) the ligands comprise multimers of alkali-stabilized Protein A domains, and b) the porous support comprises cross-linked polymer particles having a volume-weighted median diameter (d50,v) of 56-70 micrometers and a dry solids weight of 55-80 mg/ml.
Public/Granted literature
- US20200071353A1 Separation Matrix Public/Granted day:2020-03-05
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