- 专利标题： Charge-tagged nucleotides and methods of use thereof
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申请号： US16627035申请日： 2019-02-19
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公开(公告)号： US10851131B2公开(公告)日： 2020-12-01
- 发明人: Jeffrey Mandell , Silvia Gravina , Sergio Peisajovich , Kaitlin Pugliese , Yin Nah Teo , Xiangyuan Yang , Maria Candelaria Rogert Bacigalupo
- 申请人： ILLUMINA, INC. , ILLUMINA SINGAPORE PTE. LTD.
- 申请人地址： US CA San Diego SG Singapore
- 专利权人： ILLUMINA, INC.,ILLUMINA SINGAPORE PTE. LTD.
- 当前专利权人： ILLUMINA, INC.,ILLUMINA SINGAPORE PTE. LTD.
- 当前专利权人地址： US CA San Diego SG Singapore
- 代理机构： Heslin Rothenberg Farley & Mesiti P.C.
- 国际申请： PCT/US2019/018565 WO 20190219
- 国际公布： WO2019/161381 WO 20190822
- 主分类号： C07H21/00
- IPC分类号： C07H21/00 ; C12Q1/6869 ; C40B70/00
摘要：
Provided is a method including detecting an incorporation of a labelled nucleotide into a nascent polynucleotide strand complementary to a template polynucleotide strand by a polymerase, wherein the polymerase is tethered to a solid support conductive channel by a tether and the labelled nucleotides is a compound of Formula I:
公开/授权文献
- US20200123193A1 CHARGE-TAGGED NUCLEOTIDES AND METHODS OF USE THEREOF 公开/授权日：2020-04-23
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