Invention Grant
- Patent Title: Charge-tagged nucleotides and methods of use thereof
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Application No.: US16627035Application Date: 2019-02-19
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Publication No.: US10851131B2Publication Date: 2020-12-01
- Inventor: Jeffrey Mandell , Silvia Gravina , Sergio Peisajovich , Kaitlin Pugliese , Yin Nah Teo , Xiangyuan Yang , Maria Candelaria Rogert Bacigalupo
- Applicant: ILLUMINA, INC. , ILLUMINA SINGAPORE PTE. LTD.
- Applicant Address: US CA San Diego SG Singapore
- Assignee: ILLUMINA, INC.,ILLUMINA SINGAPORE PTE. LTD.
- Current Assignee: ILLUMINA, INC.,ILLUMINA SINGAPORE PTE. LTD.
- Current Assignee Address: US CA San Diego SG Singapore
- Agency: Heslin Rothenberg Farley & Mesiti P.C.
- International Application: PCT/US2019/018565 WO 20190219
- International Announcement: WO2019/161381 WO 20190822
- Main IPC: C07H21/00
- IPC: C07H21/00 ; C12Q1/6869 ; C40B70/00
Abstract:
Provided is a method including detecting an incorporation of a labelled nucleotide into a nascent polynucleotide strand complementary to a template polynucleotide strand by a polymerase, wherein the polymerase is tethered to a solid support conductive channel by a tether and the labelled nucleotides is a compound of Formula I:
Public/Granted literature
- US20200123193A1 CHARGE-TAGGED NUCLEOTIDES AND METHODS OF USE THEREOF Public/Granted day:2020-04-23
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