Invention Grant
- Patent Title: Libraries of modified fibronectin type III tenth domain-containing polypeptides
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Application No.: US15826196Application Date: 2017-11-29
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Publication No.: US10995131B2Publication Date: 2021-05-04
- Inventor: Yan Chen , Elena Getmanova , Martin C. Wright , Alan S. Harris , Ai Ching Lim , Jochem Gokemeijer , Lin Sun , Michael Wittekind
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Christopher L. Frank
- Main IPC: C07K14/78
- IPC: C07K14/78 ; C07K19/00 ; C40B40/08 ; C40B40/10 ; C12N15/10 ; C12N15/09 ; A61K38/39 ; C07H21/04 ; A61K38/00 ; A61K39/00 ; C07K14/47 ; C07K14/52 ; C07K16/28 ; C07K16/30
Abstract:
The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.
Public/Granted literature
- US20180162926A1 INHIBITORS OF TYPE 2 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTORS Public/Granted day:2018-06-14
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