Invention Grant
- Patent Title: Quinazolines as potassium ion channel inhibitors
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Application No.: US16864825Application Date: 2020-05-01
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Publication No.: US11008306B2Publication Date: 2021-05-18
- Inventor: James A. Johnson , John Lloyd , Heather Finlay , James Neels , Naveen Kumar Dhondi , Prashantha Gunaga , Abhisek Banerjee , Ashokkumar Adisechan
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agent Mary K. VanAtten
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D239/95 ; C07D401/12 ; C07D403/04 ; C07D403/12 ; C07D407/12 ; C07D413/14 ; C07D417/12 ; C07D417/14 ; A61K31/517 ; A61K31/5377 ; A61K31/549 ; A61K45/06 ; C07D239/94 ; C07D405/12 ; C07D471/04 ; C07D513/04

Abstract:
A compound of formula I wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
Public/Granted literature
- US20200255407A1 QUINAZOLINES AS POTASSIUM ION CHANNEL INHIBITORS Public/Granted day:2020-08-13
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