Invention Grant
- Patent Title: Methods of cleaning a protein A based affinity chromatography column
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Application No.: US14912440Application Date: 2014-06-19
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Publication No.: US11014129B2Publication Date: 2021-05-25
- Inventor: Nanying Bian , Sapna Mehtani , John Dana Hubbard
- Applicant: EMD Millipore Corporation
- Applicant Address: US MA Burlington
- Assignee: EMD Millipore Corporation
- Current Assignee: EMD Millipore Corporation
- Current Assignee Address: US MA Burlington
- Agency: EMD Millipore Corporation
- International Application: PCT/US2014/043095 WO 20140619
- International Announcement: WO2015/034566 WO 20150312
- Main IPC: B08B9/027
- IPC: B08B9/027 ; C07K1/22 ; A61L2/18 ; B08B3/08
Abstract:
The present invention provides methods for cleaning a Protein A chromatography column employing a media comprising a Protein A ligand derived from the C domain of Staphylococcus aureus, such that the column can be cleaned using both acidic and alkaline solutions.
Public/Granted literature
- US20160193633A1 PROTEIN A CHROMATOGRAPHY Public/Granted day:2016-07-07
Information query
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