- 专利标题: Immunoregulatory agents
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申请号: US15524113申请日: 2015-11-05
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公开(公告)号: US11242319B2公开(公告)日: 2022-02-08
- 发明人: Hilary Plake Beck , Juan Carlos Jaen , Maksim Osipov , Jay Patrick Powers , Maureen Kay Reilly , Hunter Paul Shunatona , James Ross Walker , Mikhail Zibinsky , James Aaron Balog , David K. Williams , Weiwei Guo
- 申请人: FLEXUS BIOSCIENCES, INC.
- 申请人地址: US NJ Princeton
- 专利权人: FLEXUS BIOSCIENCES, INC.
- 当前专利权人: FLEXUS BIOSCIENCES, INC.
- 当前专利权人地址: US NJ Princeton
- 代理机构: BakerHostetler
- 国际申请: PCT/US2015/059271 WO 20151105
- 国际公布: WO2016/073738 WO 20160512
- 主分类号: C07D213/75
- IPC分类号: C07D213/75 ; A61K45/06 ; A61K31/167 ; C07C255/60 ; C07C317/40 ; C07D239/42 ; C07C233/15 ; C07D295/155 ; C07C233/29 ; C07C237/22 ; C07C233/66 ; C07D213/56 ; C07C321/28 ; C07D295/15 ; C07C235/26 ; A61K31/195 ; C07C255/57 ; C07C235/38 ; C07D207/27 ; C07D231/12 ; C07C317/44 ; C07C237/20 ; C07D309/06 ; C07D309/04 ; C07C235/36 ; C07D317/46 ; C07D277/30 ; A61K31/426 ; A61K39/39 ; A61P35/00 ; A61P37/06 ; A61K31/277 ; A61K31/343 ; A61K31/44 ; A61K31/505 ; A61K31/5375 ; C07C233/11 ; C07C233/28 ; C07C323/41 ; C07D317/66 ; A61K39/00
摘要:
Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
公开/授权文献
- US20190092729A1 IMMUNOREGULATORY AGENTS 公开/授权日:2019-03-28
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