Invention Grant
- Patent Title: Compositions and methods for inducing thrombopoiesis
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Application No.: US16392685Application Date: 2019-04-24
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Publication No.: US11273201B2Publication Date: 2022-03-15
- Inventor: Dina Ben Yehuda , Ihab Abd-Elrahman , Riki Perlman , Marjorie Pick
- Applicant: Hadasit Medical Research Services and Development Ltd.
- Applicant Address: IL Jerusalem
- Assignee: Hadasit Medical Research Services and Development Ltd.
- Current Assignee: Hadasit Medical Research Services and Development Ltd.
- Current Assignee Address: IL Jerusalem
- Main IPC: C12N15/85
- IPC: C12N15/85 ; A61K38/17 ; C12N5/078 ; C12N5/0789 ; A61K45/06 ; A61K35/28 ; A61K35/545
Abstract:
Methods of inducing thrombopoiesis and/or treating thrombocytopenia in a subject are provided. Accordingly there is provided a method comprising contacting stem cells with a differentiation potential towards platelets or hematopoietic progenitor cells derived therefrom with Livin, thereby inducing thrombopoiesis. Also provided is a method comprising contacting cells with a differentiation potential towards platelets with tLivin, thereby inducing thrombopoiesis. Also provided are compositions and isolated population of cells for inducing thrombopoiesis and/or treating thrombocytopenia in a subject.
Public/Granted literature
- US20190247464A1 COMPOSITIONS AND METHODS FOR INDUCING THROMBOPOIESIS Public/Granted day:2019-08-15
Information query
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