Invention Grant
- Patent Title: 4H-pyran compounds as insulin-regulated aminopeptidase (IRAP) inhibitors
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Application No.: US15572554Application Date: 2016-05-06
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Publication No.: US11306066B2Publication Date: 2022-04-19
- Inventor: Siew Yeen Chai , Philip Thompson , Simon Mountford , Michael W. Parker
- Applicant: Monash University , The Florey Institute of Neuroscience and Mental Health , St. Vincent's Institute of Medical Research
- Applicant Address: AU Clayton; AU Melbourne; AU Fitzroy
- Assignee: Monash University,The Florey Institute of Neuroscience and Mental Health,St. Vincent's Institute of Medical Research
- Current Assignee: Monash University,The Florey Institute of Neuroscience and Mental Health,St. Vincent's Institute of Medical Research
- Current Assignee Address: AU Clayton; AU Melbourne; AU Fitzroy
- Agency: Adsero IP
- Priority: AU2015901676 20150508
- International Application: PCT/AU2016/050332 WO 20160506
- International Announcement: WO2016/179645 WO 20161117
- Main IPC: A61K31/351
- IPC: A61K31/351 ; A61K31/352 ; A61K31/35 ; C07D309/32 ; C07D311/74 ; C07D311/02 ; C07D311/00 ; A61P25/28 ; C07D405/04 ; C07D405/10 ; C07D493/04 ; C07D407/10 ; C07D409/10
Abstract:
The present disclosure relates generally, but not exclusively, to compounds and their use in therapy, to compositions and agents comprising said compounds, to methods of treatment using said compounds, and their use in the manufacture of medicaments. The disclosure further relates to inhibitors of IRAP and their use in the treatment or prevention of Alzheimer's disease and the treatment and prevention of memory and cognitive disorders.
Public/Granted literature
- US20180170891A1 4H-Pyran Compounds as Insulin-Regulated Aminopeptidase (IRAP) Inhibitors Public/Granted day:2018-06-21
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