Invention Grant
- Patent Title: Chromatography method for quantifying a nonionic surfactant in a composition comprising the non-ionic surfactant and a polypeptide
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Application No.: US16275849Application Date: 2019-02-14
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Publication No.: US11333644B2Publication Date: 2022-05-17
- Inventor: Mary Montti , Richard L. Beardsley , Michael S. Chinn
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Morrison & Foerster LLP
- Main IPC: A61K47/10
- IPC: A61K47/10 ; A61K47/26 ; B01D15/38 ; G01N30/36 ; G01N30/96
Abstract:
The invention provides methods for quantifying a non-ionic surfactant in a composition comprising a polypeptide and the non-ionic surfactant, where the quantification exhibits reduced interference between the non-ionic surfactant and the polypeptide. Also provided are methods where the composition further includes N-acetyl tryptophan, and the quantification exhibits reduced interference between the non-ionic surfactant, the polypeptide, and N-acetyl tryptophan.
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Information query
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