Invention Grant
- Patent Title: Efficient crystallization process for preparing ultrapure Treprostinil and crystal prepared therefrom
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Application No.: US16720711Application Date: 2019-12-19
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Publication No.: US11339110B2Publication Date: 2022-05-24
- Inventor: Shih-Yi Wei , Jian-Bang Jheng , Ming-Kun Hsu , Min-Kuan Hsu , Tzyh-Mann Wei
- Applicant: CHIROGATE INTERNATIONAL INC.
- Applicant Address: TW Yangmei
- Assignee: CHIROGATE INTERNATIONAL INC.
- Current Assignee: CHIROGATE INTERNATIONAL INC.
- Current Assignee Address: TW Yangmei
- Agency: Ladas & Parry LLP
- Main IPC: C07C59/72
- IPC: C07C59/72 ; C07C51/43

Abstract:
There is provided a crystalline Form I of anhydrous Treprostinil and processes for the preparation thereof. The crystalline Form I of anhydrous Treprostnil is a stable crystalline form, which can provide steady physicochemical properties for pharmaceutical formulations, and is advantageous widely and safety used in storage, shipment, and handling for commercially considerations.
Public/Granted literature
- US20210188757A1 EFFICIENT CRYSTALLIZATION PROCESS FOR PREPARING ULTRAPURE TREPROSTINIL AND CRYSTAL PREPARED THEREFROM Public/Granted day:2021-06-24
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