Invention Grant
- Patent Title: Reduced viscosity protein pharmaceutical formulations
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Application No.: US16337325Application Date: 2017-10-06
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Publication No.: US11459401B2Publication Date: 2022-10-04
- Inventor: Alona Teran , Qahera Munaim , Nazer Khalaf , Rahul Rajan Kaushik , Christi L. Clogston , Twinkle R. Christian , William J. Callahan
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Julie J. Hong
- International Application: PCT/US2017/055620 WO 20171006
- International Announcement: WO2018/067987 WO 20180412
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/40 ; A61K9/19 ; A61K47/18 ; A61K47/22 ; A61K47/24 ; A61K47/26 ; A61K47/42

Abstract:
Described herein are therapeutic protein formulations comprising N-methyl pyrrolidone (NMP), methods related to reducing viscosity of pharmaceutical formulations and methods related to stabilizing pharmaceutical formulations using NMP.
Public/Granted literature
- US20200024363A1 REDUCED VISCOSITY PROTEIN PHARMACEUTICAL FORMULATIONS Public/Granted day:2020-01-23
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