Invention Grant
- Patent Title: Removal of leaked affinity purification ligand
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Application No.: US17554865Application Date: 2021-12-17
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Publication No.: US11492372B2Publication Date: 2022-11-08
- Inventor: Samuel Ray Trejo , Robert Perry Brake
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Main IPC: B01D15/36
- IPC: B01D15/36 ; B01D15/38 ; C07K1/18 ; C07K16/00 ; C07K1/22 ; C07K14/705 ; C07K14/715 ; B01D15/18
Abstract:
The invention provides for the removal of a large fraction of contaminants from protein preparations while maintaining a high level of recovery using tentacle anion exchange matrix chromatography medium. Using the methods of the invention, leached affinity chromatography contaminants can be removed from recombinant protein preparations.
Public/Granted literature
- US20220144886A1 REMOVAL OF LEAKED AFFINITY PURIFICATION LIGAND Public/Granted day:2022-05-12
Information query
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