- 专利标题: DNA sequencing by synthesis using modified nucleotides and nanopore detection
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申请号: US16653278申请日: 2019-10-15
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公开(公告)号: US11499186B2公开(公告)日: 2022-11-15
- 发明人: Jingyue Ju , Shiv Kumar , Zengmin Li , Chuanjuan Tao , Minchen Chien , James J. Russo , Sergey Kalachikov , Ken Shepard , Jacob Karl Rosenstein
- 申请人: Jingyue Ju , Shiv Kumar , Zengmin Li , Chuanjuan Tao , Minchen Chien , James J. Russo , Sergey Kalachikov , Ken Shepard , Jacob Karl Rosenstein
- 申请人地址: US NJ Englewood Cliffs; US NJ Belle Mead; US NY Flushing; US NY New York; US NJ Tenafly; US NY New York; US NY New York; US NY Ossining; US RI Providence
- 专利权人: Jingyue Ju,Shiv Kumar,Zengmin Li,Chuanjuan Tao,Minchen Chien,James J. Russo,Sergey Kalachikov,Ken Shepard,Jacob Karl Rosenstein
- 当前专利权人: Jingyue Ju,Shiv Kumar,Zengmin Li,Chuanjuan Tao,Minchen Chien,James J. Russo,Sergey Kalachikov,Ken Shepard,Jacob Karl Rosenstein
- 当前专利权人地址: US NJ Englewood Cliffs; US NJ Belle Mead; US NY Flushing; US NY New York; US NJ Tenafly; US NY New York; US NY New York; US NY Ossining; US RI Providence
- 代理商 Gary J. Gershik
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C12Q1/6869 ; C07H19/10 ; C07H21/00 ; G01N33/487
摘要:
This disclosure is related to a method of sequencing a single-stranded DNA using deoxynucleotide polyphosphate analogues and translocation of tags from incorporated deoxynucleotide polyphosphate analogues through a nanopore.