- 专利标题： 2-(morpholin-4-yl)-1,7-naphthyridines
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申请号： US16999832申请日： 2020-08-21
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公开(公告)号： US11529356B2公开(公告)日： 2022-12-20
- 发明人: Lars Wortmann , Ulrich Lücking , Julien Lefranc , Hans Briem , Marcus Koppitz , Knut Eis , Franz Von Nussbaum , Benjamin Bader , Antje Margret Wengner , Gerhard Siemeister , Wilhelm Bone , Philip Lienau , Joanna Grudzinska-Goebel , Dieter Moosmayer , Uwe Eberspächer , Hans Schick
- 申请人： Bayer Pharma Aktiengesellschaft
- 申请人地址： DE Berlin
- 专利权人： Bayer Pharma Aktiengesellschaft
- 当前专利权人： Bayer Pharma Aktiengesellschaft
- 当前专利权人地址： DE Berlin
- 代理机构： Morrison & Foerster LLP
- 优先权： EP14179692 20140804,EP15159342 20150317
- 主分类号： A61K31/4375
- IPC分类号： A61K31/4375 ; A61K31/5377 ; A61K31/4155 ; C07D471/04 ; C07D519/00 ; C07D413/14 ; A61P35/00 ; A61P35/02 ; A61K31/541 ; A61K31/5386 ; A61K31/55 ; A61K31/675 ; A61K45/06 ; C07D491/22 ; C07F9/6561
摘要：
The present invention relates to substituted 2-(morpholin-4-yl)-1,7-naphthyridine compounds of general formula (I) or (Ib), to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative disease as a sole agent or in combination with other active ingredients.
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