- 专利标题: Heterocyclic modulators of lipid synthesis
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申请号: US16838753申请日: 2020-04-02
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公开(公告)号: US11622968B2公开(公告)日: 2023-04-11
- 发明人: Douglas Buckley , Gregory Duke , Allan S. Wagman , Marc Evanchik , Robert S. McDowell
- 申请人: Sagimet Biosciences Inc.
- 申请人地址: US CA San Mateo
- 专利权人: Sagimet Biosciences Inc.
- 当前专利权人: Sagimet Biosciences Inc.
- 当前专利权人地址: US CA San Mateo
- 代理机构: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- 代理商 Dean Farmer; Christine C. Pemberton
- 主分类号: A61K31/55
- IPC分类号: A61K31/55 ; A61K31/454 ; A61K31/4545 ; A61K31/5377 ; A61K31/496 ; A61K31/501 ; A61K31/506 ; A61K31/437 ; A61K31/4525 ; C07D491/048 ; C07D401/14 ; C07D491/10 ; C07D413/10 ; C07D401/06 ; C07D405/04 ; C07D487/04 ; C07D413/14 ; C07D491/107 ; C07D401/04 ; C07D405/14 ; C07D405/10 ; C07D405/12 ; C07D471/04 ; C07D401/12 ; C07D491/052 ; C07D401/10 ; C07D513/04 ; A61K31/453 ; A61K31/451
摘要:
Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
公开/授权文献
- US20220296605A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS 公开/授权日:2022-09-22
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