- 专利标题: Coating a bioreactor in a cell expansion system
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申请号: US16845791申请日: 2020-04-10
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公开(公告)号: US11634677B2公开(公告)日: 2023-04-25
- 发明人: Nathan D. Frank , Brian J. Nankervis , Dennis J. Hlavinka , Thomas G. Dilorenzo
- 申请人: Terumo BCT, Inc.
- 申请人地址: US CO Lakewood
- 专利权人: Terumo BCT, Inc.
- 当前专利权人: Terumo BCT, Inc.
- 当前专利权人地址: US CO Lakewood
- 代理机构: Harness, Dickey & Pierce, P.L.C.
- 主分类号: C12M3/00
- IPC分类号: C12M3/00 ; C12M1/00 ; C12M1/36 ; C12M1/34 ; C12Q3/00 ; C12N5/0775 ; C12M1/12 ; B05D7/22 ; C12M3/04
摘要:
Embodiments described herein generally provide for the expansion of cells in a cell expansion system using an active promotion of a coating agent(s) to a cell growth surface in some embodiments. A coating agent may be applied to a surface, such as the cell growth surface of a hollow fiber in a bioreactor, by controlling the movement of a fluid in which a coating agent is suspended, by changing flow rates, by changing flow directions, by rotation of the bioreactor, and/or combinations thereof.
公开/授权文献
- US20200239822A1 Coating a Bioreactor 公开/授权日:2020-07-30