Invention Grant
- Patent Title: Silvestrol antibody-drug conjugates and methods of use
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Application No.: US16827083Application Date: 2020-03-23
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Publication No.: US11648315B2Publication Date: 2023-05-16
- Inventor: Thomas Pillow , Andrew G. Polson , Bing Zheng
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Viksnins Harris Padys Malen LLP
- The original application number of the division: US15613477 2017.06.05
- Main IPC: A61K31/357
- IPC: A61K31/357 ; A61K45/06 ; C07D407/12 ; C07K19/00 ; G01N33/567 ; A61K47/54 ; A61K47/68 ; A61K39/00
Abstract:
The invention relates generally to a silvestrol molecule activated with a leaving group. The invention further relates generally to an antibody-drug conjugate comprising an antibody conjugated by a linker to one or more silvestrol drug moieties and methods of treatment.
Public/Granted literature
- US20200222545A1 SILVESTROL ANTIBODY-DRUG CONJUGATES AND METHODS OF USE Public/Granted day:2020-07-16
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