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公开(公告)号:US20180044420A1
公开(公告)日:2018-02-15
申请号:US15657471
申请日:2017-07-24
Applicant: Genentech, Inc.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: C07K16/28 , A61K47/68 , A61K51/10 , A61K31/706 , G01N33/574 , C07K16/30 , A61K31/5517
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20170362318A1
公开(公告)日:2017-12-21
申请号:US15406583
申请日:2017-01-13
Applicant: GENENTECH, INC.
Inventor: Craig Crowley , Frederic J. De Sauvage , Dan L. Eaton , Allen Ebens, JR. , Kristi Elkins , Jo-Anne S. Hongo , Jagath Reddy Junutula , Andrew Polson , Sarajane Ross , Victoria Smith , Richard L. Vandlen , Bing Zheng
IPC: C07K16/28 , G01N33/574 , C07K16/30 , A61K47/68 , C07K14/705 , A61K38/00 , A61K39/00
CPC classification number: C07K16/2803 , A61K38/00 , A61K47/6817 , A61K47/6851 , A61K2039/505 , C07K14/705 , C07K16/30 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/624 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/574
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20170348422A1
公开(公告)日:2017-12-07
申请号:US15613477
申请日:2017-06-05
Applicant: Genentech, Inc.
Inventor: Thomas Pillow , Andrew G. Polson , Bing Zheng
IPC: A61K47/54 , A61K31/357 , G01N33/567 , A61K39/00
CPC classification number: A61K47/541 , A61K31/357 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6855 , A61K2039/572 , A61K2039/627 , C07D407/12 , C07K19/00 , G01N33/567
Abstract: The invention relates generally to a silvestrol molecule activated with a leaving group. The invention further relates generally to an antibody-drug conjugate comprising an antibody conjugated by a linker to one or more silvestrol drug moieties and methods of treatment.
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公开(公告)号:US20160075787A1
公开(公告)日:2016-03-17
申请号:US14852369
申请日:2015-09-11
Applicant: GENENTECH, INC.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang
IPC: C07K16/28 , A61K31/706 , G01N33/574 , A61K31/5517 , A61K51/10 , C07K16/30 , A61K47/48
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗CLL-1抗体和免疫缀合物及其使用方法。
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公开(公告)号:US20130089555A1
公开(公告)日:2013-04-11
申请号:US13682581
申请日:2012-11-20
Applicant: Genentech, Inc.
Inventor: Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: C07K16/28 , A61K38/19 , A61K31/56 , A61K39/00 , A61K31/69 , A61K33/24 , A61K31/138 , A61K31/4196 , A61K31/5685 , A61K31/4745 , A61K31/568 , A61K31/517 , A61K39/395 , A61K31/454
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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6.ANTI-FcRH5 ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE 审中-公开
Title translation: ANTI-FcRH5抗体和免疫球蛋白及其使用方法公开(公告)号:US20130089497A1
公开(公告)日:2013-04-11
申请号:US13673565
申请日:2012-11-09
Applicant: Genentech, Inc.
Inventor: Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: A61K39/395 , A61K31/69
CPC classification number: A61K39/3955 , A61K31/69 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K16/283 , C07K2317/24 , C07K2317/92 , A61K2300/00
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物,以及使用这些物质组合物的方法。
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公开(公告)号:US10266597B2
公开(公告)日:2019-04-23
申请号:US15657472
申请日:2017-07-24
Applicant: Genentech, Inc.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: A61K39/395 , C07K16/28 , A61K31/5517 , A61K31/706 , A61K51/10 , C07K16/30 , G01N33/574 , A61K47/68
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20180201679A1
公开(公告)日:2018-07-19
申请号:US15803495
申请日:2017-11-03
Applicant: GENENTECH, INC.
Inventor: Yvonne Chen , Mark Dennis , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
CPC classification number: C07K16/2803 , A61K39/39541 , A61K39/39558 , A61K47/6849 , A61K51/1027 , A61K2039/505 , C07K16/2896 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/92 , Y02A50/412
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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9.Anti-FcRH5 antibodies and immunoconjugates and methods of use 有权
Title translation: 抗FcRH5抗体和免疫缀合物及其使用方法公开(公告)号:US09017951B2
公开(公告)日:2015-04-28
申请号:US13673565
申请日:2012-11-09
Applicant: Genentech, Inc.
Inventor: Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: G01N33/53 , G01N33/574 , A61K39/395 , A61K45/06 , C07K16/28 , A61K31/69 , A61K39/00
CPC classification number: A61K39/3955 , A61K31/69 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K16/283 , C07K2317/24 , C07K2317/92 , A61K2300/00
Abstract: A method of determining the presence of FcRH5 in a biological sample suspected of containing FcRH5 is provided comprising exposing the biological sample to an isolated monoclonal anti-FcRH5 antibody.
Abstract translation: 提供了一种确定怀疑含有FcRH5的生物样品中FcRH5存在的方法,包括将生物样品暴露于分离的单克隆抗FcRH5抗体。
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公开(公告)号:US20140030281A1
公开(公告)日:2014-01-30
申请号:US13936284
申请日:2013-07-08
Applicant: Genentech, Inc.
Inventor: Paul Polakis , Andrew Polson , Susan Diane Spencer , Shang-Fan Yu , Bing Zheng
IPC: A61K47/48 , A61K45/06 , A61K31/706
CPC classification number: A61K47/6807 , A61K31/706 , A61K45/06 , A61K47/6809 , A61K47/6849 , A61K47/6867
Abstract: The invention provides anti-CD22 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗CD22抗体和免疫缀合物及其使用方法。
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