- Patent Title: Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
-
Application No.: US16411793Application Date: 2019-05-14
-
Publication No.: US11649469B2Publication Date: 2023-05-16
- Inventor: George M. Church , Kevin M. Esvelt , Prashant G. Mali
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Banner & Witcoff, Ltd.
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N15/90 ; C12N15/85 ; C12N9/22 ; C12N15/113 ; C07K2/00 ; C12N15/11
Abstract:
Methods of modulating expression of a target nucleic acid in a cell are provided including use of multiple orthogonal Cas9 proteins to simultaneously and independently regulate corresponding genes or simultaneously and independently edit corresponding genes.
Information query
IPC分类:
