Invention Grant
- Patent Title: Biphenyl amides with modified ether groups as HSP90 inhibitors and HSP70 inducers
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Application No.: US17375882Application Date: 2021-07-14
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Publication No.: US11708319B2Publication Date: 2023-07-25
- Inventor: Brian S. J. Blagg , Rick T. Dobrowsky , Mercy Anyika
- Applicant: THE UNIVERSITY OF KANSAS
- Applicant Address: US KS Lawrence
- Assignee: UNIVERSITY OF KANSAS
- Current Assignee: UNIVERSITY OF KANSAS
- Current Assignee Address: US KS Lawrence
- Agency: Parker Highlander PLLC
- The original application number of the division: US16776091 2020.01.29
- Main IPC: C07D311/12
- IPC: C07D311/12 ; C07C233/18 ; C07D309/10 ; C07H15/203 ; C07D307/20 ; C07D311/08 ; C07D311/16

Abstract:
Provided herein are compounds of the formulas:
wherein: n, X2, R3, R3′, R4, R4′, R5, R5′, R6, and R6′ are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds may be used for the treatment of diseases, including diabetic peripheral neuropathy or cancer.
wherein: n, X2, R3, R3′, R4, R4′, R5, R5′, R6, and R6′ are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds may be used for the treatment of diseases, including diabetic peripheral neuropathy or cancer.
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