- 专利标题： Cas13b orthologues CRISPR enzymes and systems
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申请号： US16493464申请日： 2018-03-15
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公开(公告)号： US11739308B2公开(公告)日： 2023-08-29
- 发明人: David Benjamin Turitz Cox , Neena Pyzocha , Feng Zhang
- 申请人： The Broad Institute, Inc. , Massachusetts Institute of Technology
- 申请人地址： US MA Cambridge
- 专利权人： The Broad Institute, Inc.,Massachusetts Institute of Technology
- 当前专利权人： The Broad Institute, Inc.,Massachusetts Institute of Technology
- 当前专利权人地址： US MA Cambridge; US MA Cambridge
- 代理机构： Johnson, Marcou, Isaacs & Nix, LL
- 代理商 F. Brent Nix, Esq.
- 国际申请： PCT/US2018/022751 2018.03.15
- 国际公布： WO2018/170333A 2018.09.20
- 进入国家日期： 2019-09-12
- 主分类号： C12N9/22
- IPC分类号： C12N9/22 ; C12N15/86
摘要：
The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting Cas13b effector protein and at least one targeting nucleic acid component like a guide RNA or crRNA.
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