- 专利标题: Human lymphoid tissue-on-chip
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申请号: US17730615申请日: 2022-04-27
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公开(公告)号: US11865536B2公开(公告)日: 2024-01-09
- 发明人: Girija Goyal , Donald E. Ingber
- 申请人: President and Fellows of Harvard College
- 申请人地址: US MA Cambridge
- 专利权人: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- 当前专利权人: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- 当前专利权人地址: US MA Cambridge
- 代理机构: NIXON PEABODY LLP
- 主分类号: B01L3/00
- IPC分类号: B01L3/00 ; C12N5/0781 ; C12N5/0783 ; A61K35/28 ; A61P35/00 ; A61K35/17 ; C12M3/06 ; A61P37/04 ; C12M3/00 ; A61P7/00 ; C12N5/00 ; C12N5/0786 ; C12N5/078 ; C12N5/071 ; C12N5/09 ; G01N33/50
摘要:
An organ-on-a-chip microfluidic device is disclosed that mimics a human lymph node and/or human lymphoid tissue. The device can include cells from human blood and lymphatic tissue, include an extracellular matrix for the development of immune system components, and provide for the perfusion of fluids and solids resembling blood and lymphatic fluid within micrometer sized channels.
公开/授权文献
- US20220250055A1 HUMAN LYMPHOID TISSUE-ON-CHIP 公开/授权日:2022-08-11
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