Invention Grant
- Patent Title: On-column viral inactivation methods
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Application No.: US18153669Application Date: 2023-01-12
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Publication No.: US12134632B2Publication Date: 2024-11-05
- Inventor: Glen Bolton , Keith Selvitelli
- Applicant: BIOVERATIV THERAPEUTICS INC.
- Applicant Address: US MA Waltham
- Assignee: BIOVERATIV THERAPEUTICS INC.
- Current Assignee: BIOVERATIV THERAPEUTICS INC.
- Current Assignee Address: US MA Waltham
- Agency: LATHROP GPM LLP
- Agent James H. Velema, Esq.
- Main IPC: A61L2/00
- IPC: A61L2/00 ; A61K35/14 ; A61K35/16 ; A61K38/00 ; C07K1/16 ; C07K1/22 ; C07K14/755 ; C07K16/06
Abstract:
The present invention is directed to a method of inactivating virus that is present during production of a polypeptide of interest. In particular, the present invention is directed to a method of on-column virus inactivation using a low pH and high salt wash solution that effectively inactivates viruses with minimum recovery loss of the polypeptide.
Public/Granted literature
- US20230331774A1 ON-COLUMN VIRAL INACTIVATION METHODS Public/Granted day:2023-10-19
Information query
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