Methods and apparatus relating to loop driven region based frontend translation control for performant and secure data-space guided micro-sequencing are described. In an embodiment, Data-space Translation Logic (DTL) circuitry receives a static input and a dynamic input and generates one or more outputs based at least in part on the static input and the dynamic input. A frontend counter generates a count value for the dynamic input based at least in part on an incremented/decremented counter value and a next counter value from the DTL circuitry. The DTL circuitry is capable to receive a new dynamic input prior to consumption of the one or more outputs. Other embodiments are also disclosed and claimed.