发明申请
- 专利标题: Chlamydia pmp proteins, gene sequences and uses thereof
- 专利标题(中): 衣原体pmp蛋白,基因序列及其用途
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申请号: US10398248申请日: 2003-08-01
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公开(公告)号: US20040037846A1公开(公告)日: 2004-02-26
- 发明人: W. James Jackson
- 主分类号: C07K014/295
- IPC分类号: C07K014/295 ; C12Q001/68 ; C07H021/04 ; A61K039/02 ; C12P021/02 ; C12N001/21
摘要:
The invention discloses the Chlamydia PMPE and PMPI polypeptide, polypeptides derived therefrp, (PMP-derived polypeptides), nucleotide sequences encoding said polypeptides, antibodies that specifically bind the PMP polypeptides and PMP-derived polypeptides and T-cells specific for PMP polypeptides and PMP-derived polypeptides. Also disclosed are prophylactic and therapeutic compositions, including immunogenic compositions, e.g., vaccines, comprising PMP polypeptides or PMP-derived polypeptides or antibodies thereto. The invention additionally discloses methods of inducing in animals an immune response to Chlamydia cells, Chlamydia elementary bodies, and/or cells expressing Chlamydial proteins, e.g., cell infected with Chlamydia.
公开/授权文献
- US07731980B2 Chlamydia PMP proteins, gene sequences and uses thereof 公开/授权日:2010-06-08
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