- 专利标题： Amidino compounds useful as nitric oxide synthase inhibitors
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申请号： US11032650申请日： 2005-01-10
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公开(公告)号： US20050165106A1公开(公告)日： 2005-07-28
- 发明人: Ronald Webber , Richard Durley , Alok Awasthi , Arijia Bergmanis , Kam Fok , Scott Ganser , Timothy Hagen , E. Hallinan , Donald Hansen , Brian Hickory , Pamela Manning , Michael Mao , Alan Moormann , Barnett Pitzele , Michelle Promo , Richard Schartman , Jeffrey Scholten , Jeffrey Snyder , Mihaly Toth , Mahima Trivedi , Sofya Tsymbalov , Foe Tjoeng
- 申请人： Ronald Webber , Richard Durley , Alok Awasthi , Arijia Bergmanis , Kam Fok , Scott Ganser , Timothy Hagen , E. Hallinan , Donald Hansen , Brian Hickory , Pamela Manning , Michael Mao , Alan Moormann , Barnett Pitzele , Michelle Promo , Richard Schartman , Jeffrey Scholten , Jeffrey Snyder , Mihaly Toth , Mahima Trivedi , Sofya Tsymbalov , Foe Tjoeng
- 申请人地址： US MO St. Louis
- 专利权人： Pharmacia Corporation
- 当前专利权人： Pharmacia Corporation
- 当前专利权人地址： US MO St. Louis
- 主分类号： A61P1/00
- IPC分类号： A61P1/00 ; A61K31/198 ; A61K31/4166 ; A61K31/4245 ; A61P1/02 ; A61P1/04 ; A61P1/16 ; A61P3/00 ; A61P3/08 ; A61P3/10 ; A61P7/06 ; A61P9/00 ; A61P9/02 ; A61P9/10 ; A61P11/00 ; A61P11/02 ; A61P11/06 ; A61P13/12 ; A61P15/00 ; A61P15/08 ; A61P17/00 ; A61P17/02 ; A61P17/06 ; A61P19/02 ; A61P19/04 ; A61P19/06 ; A61P21/00 ; A61P21/04 ; A61P25/00 ; A61P25/04 ; A61P25/06 ; A61P25/10 ; A61P25/14 ; A61P25/16 ; A61P25/18 ; A61P25/20 ; A61P25/22 ; A61P25/24 ; A61P25/28 ; A61P25/30 ; A61P25/32 ; A61P25/34 ; A61P25/36 ; A61P27/02 ; A61P27/06 ; A61P29/00 ; A61P31/00 ; A61P35/00 ; A61P37/02 ; A61P37/06 ; A61P39/02 ; A61P43/00 ; C07C317/48 ; C07C317/50 ; C07C323/58 ; C07C323/59 ; C07D233/76 ; C07D271/06 ; C07D271/07 ; C07D277/56
摘要：
The present invention relates to amidino compounds and salts and prodrugs thereof. In another embodiment the present invention also provides a use of the present compounds in therapy, particular as nitric oxide synthase inhibitors. In a further embodiment, the present invention provides methods of making the amidino compounds.
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