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公开(公告)号:US20050165106A1
公开(公告)日:2005-07-28
申请号:US11032650
申请日:2005-01-10
申请人: Ronald Webber , Richard Durley , Alok Awasthi , Arijia Bergmanis , Kam Fok , Scott Ganser , Timothy Hagen , E. Hallinan , Donald Hansen , Brian Hickory , Pamela Manning , Michael Mao , Alan Moormann , Barnett Pitzele , Michelle Promo , Richard Schartman , Jeffrey Scholten , Jeffrey Snyder , Mihaly Toth , Mahima Trivedi , Sofya Tsymbalov , Foe Tjoeng
发明人: Ronald Webber , Richard Durley , Alok Awasthi , Arijia Bergmanis , Kam Fok , Scott Ganser , Timothy Hagen , E. Hallinan , Donald Hansen , Brian Hickory , Pamela Manning , Michael Mao , Alan Moormann , Barnett Pitzele , Michelle Promo , Richard Schartman , Jeffrey Scholten , Jeffrey Snyder , Mihaly Toth , Mahima Trivedi , Sofya Tsymbalov , Foe Tjoeng
IPC分类号: A61P1/00 , A61K31/198 , A61K31/4166 , A61K31/4245 , A61P1/02 , A61P1/04 , A61P1/16 , A61P3/00 , A61P3/08 , A61P3/10 , A61P7/06 , A61P9/00 , A61P9/02 , A61P9/10 , A61P11/00 , A61P11/02 , A61P11/06 , A61P13/12 , A61P15/00 , A61P15/08 , A61P17/00 , A61P17/02 , A61P17/06 , A61P19/02 , A61P19/04 , A61P19/06 , A61P21/00 , A61P21/04 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/10 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P25/32 , A61P25/34 , A61P25/36 , A61P27/02 , A61P27/06 , A61P29/00 , A61P31/00 , A61P35/00 , A61P37/02 , A61P37/06 , A61P39/02 , A61P43/00 , C07C317/48 , C07C317/50 , C07C323/58 , C07C323/59 , C07D233/76 , C07D271/06 , C07D271/07 , C07D277/56
CPC分类号: C07D271/07 , C07C317/48 , C07C323/58 , C07C323/59 , C07D233/76 , C07D277/56
摘要: The present invention relates to amidino compounds and salts and prodrugs thereof. In another embodiment the present invention also provides a use of the present compounds in therapy, particular as nitric oxide synthase inhibitors. In a further embodiment, the present invention provides methods of making the amidino compounds.