发明申请
US20050170500A1 Methods for identifying risk of melanoma and treatments thereof
审中-公开
识别黑色素瘤风险的方法及其治疗方法
- 专利标题： Methods for identifying risk of melanoma and treatments thereof
- 专利标题（中）： 识别黑色素瘤风险的方法及其治疗方法
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申请号： US10704513申请日： 2003-11-06
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公开(公告)号： US20050170500A1公开(公告)日： 2005-08-04
- 发明人: Richard Roth , Matthew Nelson , Stefan Kammerer , Andreas Braun
- 申请人： Richard Roth , Matthew Nelson , Stefan Kammerer , Andreas Braun
- 主分类号： A61B
- IPC分类号： A61B20060101 ; A61K31/4745 ; A61K33/24 ; A61K35/12 ; A61K38/16 ; A61K38/17 ; A61K38/45 ; A61K39/395 ; A61K48/00 ; A61P35/00 ; C07H21/00 ; C07K14/47 ; C12N20060101 ; C12N1/00 ; C12N5/06 ; C12N9/10 ; C12N15/12 ; C12N15/54 ; C12Q1/68
摘要：
Provided herein are methods for identifying risk of melanoma in a subject and/or subjects at risk of melanoma, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating melanoma, therapeutic methods for treating melanoma in a subject and compositions comprising one or more melanoma cells and one or more CDK10, FPGT, PCLO or REPS2 directed agents. These embodiments are based upon an analysis of polymorphic variations in a CDK10, FPGT, PCLO or REPS2 nucleic acid, exemplified by nucleotide sequences of SEQ ID NO: 1, 2, 3 or 4.
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