发明申请
- 专利标题： Cancer treatment
- 专利标题（中）： 癌症治疗
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申请号： US11132756申请日： 2005-05-18
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公开(公告)号： US20050209252A1公开(公告)日： 2005-09-22
- 发明人: Che-Ming Teng , Sheng-Chu Kuo , Fang-Yu Lee , Shiow-Lin Pan , Jih-Hwa Guh
- 申请人： Che-Ming Teng , Sheng-Chu Kuo , Fang-Yu Lee , Shiow-Lin Pan , Jih-Hwa Guh
- 主分类号： C07D405/04
- IPC分类号： C07D405/04 ; A61K31/416 ; A61K31/4162 ; A61K31/4745 ; A61K31/519 ; A61P1/04 ; A61P3/06 ; A61P3/10 ; A61P9/00 ; A61P9/10 ; A61P15/00 ; A61P17/06 ; A61P19/02 ; A61P27/02 ; A61P29/00 ; A61P35/00
摘要：
This invention relates to a method for treating cancer including administrating to a subject in need thereof an effective amount of a compound of the formula: wherein, A is H or each of Ar1, Ar2, and Ar3, independently, is phenyl, thienyl, furyl, pyrrolyl, pyridinyl, or pyrimidinyl; each of R1, R2, R3, R4, R5, and R6, independently, is R, nitro, halogen, C(O)OR, C(O)SR, C(O)NRR′, (CH2)mOR, (CH2)mSR, (CH2)mNRR′, (CH2)mCN, (CH2)mC(O)OR, (CH2)mCHO, (CH2)mCH═NOR, (CH2)mC(O)N(OR)R′, N(OR)R′, or R1 and R2 together, R3 and R4 together, or R5 and R6 together are O(CH2)mO, in which each of R and R′, independently, is H or C1˜C6 alkyl; and m is 0, 1, 2, 3, 4, 5, or 6, and n is 0, 1, 2, or 3.
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