发明申请
US20050250160A1 Methods and compositions using stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents
有权
使用硬脂酰CoA去饱和酶鉴定甘油三酯还原治疗剂的方法和组合物
- 专利标题: Methods and compositions using stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents
- 专利标题(中): 使用硬脂酰CoA去饱和酶鉴定甘油三酯还原治疗剂的方法和组合物
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申请号: US11178866申请日: 2005-07-11
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公开(公告)号: US20050250160A1公开(公告)日: 2005-11-10
- 发明人: Michael Hayden , Alison Brownlie , James Ntambi , Makoto Miyazaki , Mark Gray-Keller , Alan Attie
- 申请人: Michael Hayden , Alison Brownlie , James Ntambi , Makoto Miyazaki , Mark Gray-Keller , Alan Attie
- 主分类号: G01N33/50
- IPC分类号: G01N33/50 ; A61K31/00 ; A61K31/201 ; A61K31/426 ; A61K31/4439 ; A61K45/00 ; A61K48/00 ; A61P3/06 ; A61P3/10 ; A61P9/10 ; A61P43/00 ; C07K16/40 ; C12N1/15 ; C12N1/19 ; C12N1/21 ; C12N5/10 ; C12N9/00 ; C12N9/02 ; C12N15/09 ; C12N15/113 ; C12Q1/02 ; C12Q1/25 ; C12Q1/26 ; C12Q1/68 ; G01N33/15 ; G01N33/53
摘要:
The use of screening assays based on the role of human stearoyl-CoA desaturase-1 (“hSCD1”) in human diseases, disorders or conditions relating to serum levels of triglyceride, VLDL, HDL, LDL, total cholesterol, or production of secretions from mucous membranes, monounsaturated fatty acids, wax esters, and the like, is disclosed. Also disclosed are conventions useful in the prevention and/or treatment of such diseases.
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