发明申请
- 专利标题: 157 human secreted proteins
- 专利标题(中): 157人分泌蛋白
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申请号: US10986405申请日: 2004-11-12
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公开(公告)号: US20060073561A1公开(公告)日: 2006-04-06
- 发明人: Craig Rosen , Steven Ruben , Henrik Olsen , Kevin Baker , Michele Fiscella , Ping Wei , Charles Birse , George Komatsoulis , Gil Choi , Paul Moore , Ram Gupta , Yanggu Shi
- 申请人: Craig Rosen , Steven Ruben , Henrik Olsen , Kevin Baker , Michele Fiscella , Ping Wei , Charles Birse , George Komatsoulis , Gil Choi , Paul Moore , Ram Gupta , Yanggu Shi
- 主分类号: A61K38/17
- IPC分类号: A61K38/17 ; C07K14/47 ; C07H21/04 ; C12P21/06
摘要:
The present invention relates to human secreted polypeptides, and isolated nucleic acid molecules encoding said polypeptides, useful for diagnosing and treating diseases, disorders, and/or conditions related to said human secreted proteins. Antibodies that bind these polypeptides are also encompassed by the present invention. Also encompassed by the invention are vectors, host cells, and recombinant and synthetic methods for producing said polynucleotides, polypeptides, and/or antibodies. The invention further encompasses screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further encompasses methods and compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.