- 专利标题: Paired end sequencing
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申请号: US11448462申请日: 2006-06-06
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公开(公告)号: US20060292611A1公开(公告)日: 2006-12-28
- 发明人: Jan Berka , Zhoutao Chen , Michael Egholm , Brian Godwin , Stephen Hutchison , John Leamon , Gary Sarkis , Jan Simons
- 申请人: Jan Berka , Zhoutao Chen , Michael Egholm , Brian Godwin , Stephen Hutchison , John Leamon , Gary Sarkis , Jan Simons
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C12P19/34
摘要:
The present invention provides for a method of preparing a target nucleic acid fragments to produce a smaller nucleic acid which comprises the two ends of the target nucleic acid. Specifically, the invention provides cloning and DNA manipulation strategies to isolate the two ends of a large target nucleic acid into a single small DNA construct for rapid cloning, sequencing, or amplification.
公开/授权文献
- US07601499B2 Paired end sequencing 公开/授权日:2009-10-13
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