发明申请
US20070049565A1 Combination of cell necrosis inhibitor and lithium for treating neuronal death or neurological dysfunction
审中-公开
细胞坏死抑制剂和锂的组合用于治疗神经元死亡或神经功能障碍
- 专利标题： Combination of cell necrosis inhibitor and lithium for treating neuronal death or neurological dysfunction
- 专利标题（中）： 细胞坏死抑制剂和锂的组合用于治疗神经元死亡或神经功能障碍
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申请号： US11503379申请日： 2006-08-11
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公开(公告)号： US20070049565A1公开(公告)日： 2007-03-01
- 发明人: Byoung Gwag , Young Lee , Jin Shin , Sung Cho , Jae Noh , Jae Cho , Ki Kim , Hyang Lim , Jae Lee , Han Byun
- 申请人： Byoung Gwag , Young Lee , Jin Shin , Sung Cho , Jae Noh , Jae Cho , Ki Kim , Hyang Lim , Jae Lee , Han Byun
- 申请人地址： KR Suwon-si
- 专利权人： Neurotech Pharmaceuticals Co., Ltd.
- 当前专利权人： Neurotech Pharmaceuticals Co., Ltd.
- 当前专利权人地址： KR Suwon-si
- 优先权： KR10-2005-0078028 20050824
- 主分类号： A61K31/60
- IPC分类号： A61K31/60 ; A61K31/195 ; A61K31/24 ; A61K31/137
摘要：
The present invention relates to a combination of cell necrosis inhibitor and lithium, process for the preparation of the combination, pharmaceutical formulation containing the combination and use of the combination by either concomitant or sequential administration for improvement of treatment of neuronal death or neurological dysfunction. The combination of the present invention shows a synergic effect and thus is useful for treating neurological diseases, such as amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), Alzheimer's disease, Parkinson's disease, Huntington's disease, stroke, traumatic brain injury or spinal cord injury; and for treating ocular diseases such as glaucoma, diabetic retinopathy or macular degeneration.
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