公开(公告)号：US20070298129A1

公开(公告)日：2007-12-27

申请号：US11804588

申请日：2007-05-18

申请人： Byoung Gwag ,  Young Lee ,  Jin Shin ,  Sung Cho ,  Jae Noh ,  Jae Cho ,  Ki Kim ,  Hyang Lim ,  Jae Lee ,  Han Byun ,  Sun Ko ,  Sun Son ,  Sun Park

发明人： Byoung Gwag ,  Young Lee ,  Jin Shin ,  Sung Cho ,  Jae Noh ,  Jae Cho ,  Ki Kim ,  Hyang Lim ,  Jae Lee ,  Han Byun ,  Sun Ko ,  Sun Son ,  Sun Park

IPC分类号： A61K33/00 ,  A61K31/196 ,  A61P25/00 ,  A61P25/16 ,  A61P25/28 ,  C07C229/56

CPC分类号： A61K31/137 ,  A61K31/195 ,  A61K31/24 ,  A61K31/60 ,  A61K33/00 ,  A61K45/06 ,  A61K2300/00

摘要： The present invention relates to 2-hydroxy-alkylamino-benzoic acid derivatives and to a combination of cell necrosis inhibitor and lithium, process for the preparation of the derivatives or the combination, pharmaceutical formulation containing the derivatives or the combination, and use of the derivatives or the combination by either concomitant or sequential administration for improvement of treatment of neuronal death or neurological dysfunction. The derivatives and the combination of the present invention are useful for treating neurological diseases, such as amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), spinal muscular atrophy, Alzheimer's disease, Parkinson's disease, Huntington's disease, stroke, traumatic brain injury or spinal cord injury; and for treating ocular diseases such as glaucoma, diabetic retinopathy or macular degeneration.

摘要翻译： 本发明涉及2-羟基 - 烷基氨基 - 苯甲酸衍生物和细胞坏死物抑制剂与锂的组合，制备衍生物或组合的方法，含有衍生物或组合的药物制剂及其衍生物的用途 或通过伴随或连续施用来改善神经元死亡或神经功能障碍的治疗的组合。 本发明的衍生物和组合可用于治疗神经系统疾病，例如肌萎缩性侧索硬化（ALS，Lou Gehrig's disease），脊髓性肌萎缩症，阿尔茨海默氏病，帕金森病，亨廷顿病，中风，创伤性脑损伤或脊髓 伤害 并用于治疗眼部疾病如青光眼，糖尿病性视网膜病变或黄斑变性。

公开(公告)号：US20070049565A1

公开(公告)日：2007-03-01

申请号：US11503379

申请日：2006-08-11

申请人： Byoung Gwag ,  Young Lee ,  Jin Shin ,  Sung Cho ,  Jae Noh ,  Jae Cho ,  Ki Kim ,  Hyang Lim ,  Jae Lee ,  Han Byun

发明人： Byoung Gwag ,  Young Lee ,  Jin Shin ,  Sung Cho ,  Jae Noh ,  Jae Cho ,  Ki Kim ,  Hyang Lim ,  Jae Lee ,  Han Byun

IPC分类号： A61K31/60 ,  A61K31/195 ,  A61K31/24 ,  A61K31/137

CPC分类号： A61K31/24 ,  A61K31/137 ,  A61K31/195 ,  A61K31/60 ,  A61K33/00 ,  A61K45/06 ,  A61K2300/00

摘要： The present invention relates to a combination of cell necrosis inhibitor and lithium, process for the preparation of the combination, pharmaceutical formulation containing the combination and use of the combination by either concomitant or sequential administration for improvement of treatment of neuronal death or neurological dysfunction. The combination of the present invention shows a synergic effect and thus is useful for treating neurological diseases, such as amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), Alzheimer's disease, Parkinson's disease, Huntington's disease, stroke, traumatic brain injury or spinal cord injury; and for treating ocular diseases such as glaucoma, diabetic retinopathy or macular degeneration.

摘要翻译： 本发明涉及细胞坏死抑制剂和锂的组合，制备该组合的方法，含有组合的药物制剂以及通过伴随或连续施用组合使用以改善神经元死亡或神经功能障碍的治疗。 本发明的组合显示出协同效应，因此可用于治疗诸如肌萎缩性侧索硬化（ALS，Lou Gehrig's disease），阿尔茨海默病，帕金森病，亨廷顿病，中风，创伤性脑损伤或脊髓损伤等神经疾病 ; 并用于治疗眼部疾病如青光眼，糖尿病性视网膜病变或黄斑变性。

公开(公告)号：US20070185337A1

公开(公告)日：2007-08-09

申请号：US11596580

申请日：2005-05-25

申请人： Seong-Jin Kim ,  Chung-woo Lim ,  Chang Boo ,  Jung-hoon Oh ,  Ki Kim ,  Jae Lee ,  Duk Won

发明人： Seong-Jin Kim ,  Chung-woo Lim ,  Chang Boo ,  Jung-hoon Oh ,  Ki Kim ,  Jae Lee ,  Duk Won

IPC分类号： C07D207/04

CPC分类号： C07D207/273

摘要： A process for the preparation of chiral 4-hydroxy-2-oxo-1-pyrrolidine acetamide includes adding sodium cyanide together with citric acid to a solution of chiral epichlorohydrin to obtain chiral 3-chloro-2-hydroxypropionitrile by ring opening reaction of the chiral epichlorohydrin, reacting the obtained product with an alcohol containing hydrochloride gas to obtain chiral 4-chloro-3-hydroxybutyric acid ester, and reacting the obtained product in a presence of a base with glycinamide or with glycine ester accompanied by ammonolysis with ammonia to produce the targeted chiral 4-hydroxy-2-oxo-1-pyrrolidine acetamide.

摘要翻译： 手性4-羟基-2-氧代-1-吡咯烷乙酰胺的制备方法包括将氰化钠与柠檬酸一起加入到手性表氯醇的溶液中，以通过手性的开环反应获得手性3-氯-2-羟基丙腈 将得到的产物与含有盐酸气体的醇反应，得到手性4-氯-3-羟基丁酸酯，并使得到的产物在碱的存在下与甘氨酰胺或甘氨酸酯反应，伴随着氨的氨解，生成 靶向手性4-羟基-2-氧代-1-吡咯烷乙酰胺。

公开(公告)号：US20050168417A1

公开(公告)日：2005-08-04

申请号：US11046803

申请日：2005-02-01

申请人： Won Ha ,  Hak Kim ,  Jae Lee ,  Ki Kim ,  Jung Seo ,  Hyun Kim

发明人： Won Ha ,  Hak Kim ,  Jae Lee ,  Ki Kim ,  Jung Seo ,  Hyun Kim

IPC分类号： H01L51/50 ,  G09G3/20 ,  G09G3/30 ,  G09G3/32 ,  G09G3/36 ,  H03K17/00 ,  H03M1/66 ,  H05B33/08 ,  H05B33/14

CPC分类号： G09G3/2011 ,  G09G3/2022 ,  G09G3/2081 ,  G09G3/3233 ,  G09G3/3291 ,  G09G3/3655 ,  G09G2300/0842 ,  G09G2300/0866 ,  G09G2310/027 ,  G09G2320/043

摘要： There is disclosed an electro-luminescence display device that is adaptive for preventing picture quality deterioration by operating a thin film transistor for an electro-luminescence cell drive at a non-saturation area to compensate a threshold voltage, and a driving method thereof. An electro-luminescence display device according to an embodiment of the present invention includes an electro-luminescence cell connected between a first supply voltage source and a ground voltage source to emit light by a current supplied from the first supply voltage source; a cell driver formed every intersection of gate lines and data lines and connected between the first supply voltage source and the electro-luminescence cell to control a current flowing in the pixel cell; and a pulse supplier supplies to the electro-luminescence cell a pulse amplitude modulation signal which is divided to have N (N is a natural number) numbers of different voltage levels from each other, and wherein the driving thin film transistor operates at the non-saturation region.

摘要翻译： 公开了一种电致发光显示装置，其适用于通过在非饱和区域上操作用于电致发光单元驱动的薄膜晶体管来补偿阈值电压来防止图像质量劣化，以及其驱动方法。 根据本发明实施例的电致发光显示装置包括连接在第一电源电压源和地电压源之间的电致发光单元，用于通过从第一电源电压源提供的电流发光; 连接在第一电源电压源和电致发光单元之间的每一个栅极线和数据线的交点处形成单元驱动器，以控制流过像素单元的电流; 并且脉冲供应器向电致发光单元提供被分割为彼此具有不同电压电平的N（N是自然数）个数的脉冲幅度调制信号，并且其中驱动薄膜晶体管在非易失性存储器 饱和区。

公开(公告)号：US20050142668A1

公开(公告)日：2005-06-30

申请号：US11015422

申请日：2004-12-20

申请人： Woo Cheong ,  Yong Yoo ,  Doo Cho ,  Jae Lee ,  Ki Kim ,  Jeong Suh

发明人： Woo Cheong ,  Yong Yoo ,  Doo Cho ,  Jae Lee ,  Ki Kim ,  Jeong Suh

IPC分类号： H01L21/00

CPC分类号： G11B5/3909 ,  B82Y10/00 ,  B82Y25/00 ,  B82Y40/00 ,  G01R33/093 ,  G11B5/3163 ,  G11B5/3929 ,  G11B2005/3996 ,  H01F10/3254 ,  H01F10/3268 ,  H01F41/18 ,  H01F41/20 ,  H01F41/308

摘要： Provided is a method of manufacturing a thin film magnetic head. In particular, a method of manufacturing a thin film magnetic head is provided in which a flow process of a photoresist is applied to separate a hard magnetic layer and a metal multi-layer and a photoresist is used to insulate an upper electrode from a lower electrode in manufacturing a magnetic reproduction device, thereby simplifying and optimizing a manufacturing process and significantly reducing a manufacturing time

摘要翻译： 提供一种制造薄膜磁头的方法。 特别地，提供一种制造薄膜磁头的方法，其中施加光致抗蚀剂的流动过程以分离硬磁性层和金属多层，并且使用光致抗蚀剂来使上电极与下电极绝缘 在制造磁再现装置中，从而简化和优化制造工艺并显着减少制造时间

公开(公告)号：US20050184935A1

公开(公告)日：2005-08-25

申请号：US11056189

申请日：2005-02-14

申请人： Jae Lee ,  Ki Kim ,  Hak Kim

发明人： Jae Lee ,  Ki Kim ,  Hak Kim

IPC分类号： G09G3/30 ,  G09G3/32

CPC分类号： G09G3/3216 ,  G09G2310/0248

摘要： An electro-luminescence display panel and a driving method thereof for increasing a light-emitting time of a pixel as well as reducing power consumption are disclosed. In the electro-luminescence display panel, a pixel matrix has a plurality of electro-luminescence cells connected between scan lines and data lines. A scan driver drives the scan line. A data driver pre-charges the data lines into a middle voltage of data signals and then supplies corresponding data signals.

摘要翻译： 公开了一种用于增加像素的发光时间以及降低功耗的电致发光显示面板及其驱动方法。 在电致发光显示面板中，像素矩阵具有连接在扫描线和数据线之间的多个电致发光单元。 扫描驱动程序驱动扫描线。 数据驱动器将数据线预充电成数据信号的中间电压，然后提供相应的数据信号。

公开(公告)号：US20050162071A1

公开(公告)日：2005-07-28

申请号：US10971318

申请日：2004-10-22

申请人： Jae Lee ,  Se Son ,  Young Lee ,  Jeoung Noh

发明人： Jae Lee ,  Se Son ,  Young Lee ,  Jeoung Noh

IPC分类号： H01L51/44 ,  H01L51/52 ,  H05B33/00 ,  H05B33/26

CPC分类号： H05B33/26 ,  H01L51/442 ,  H01L51/5212 ,  H01L51/5215 ,  H01L2251/308 ,  Y02E10/549

摘要： The present invention provides a light-transmitting electrode in which metal lines made of a metal with the same or superior electric conductivity to a material for the electrode are arranged linearly on the upper surface, lower surface or both surface of the electrode in the direction away from the connection part between the electrode and an electrode pad. Also, the present invention provides an electrode with a structure in which different electrically conductive compounds are alternately layered. The electrode of the present invention is excellent in transparency and electric conductivity. Also, the present invention provides organic light-emitting devices comprising the electrode.

摘要翻译： 本发明提供一种透光电极，其中与电极材料具有相同或优异的导电性的金属制成的金属线在电极的上表面，下表面或两个表面上以离开的方向直线地布置 从电极和电极焊盘之间的连接部分。 另外，本发明提供具有交替层叠不同导电性化合物的结构的电极。 本发明的电极透明性和导电性优异。 此外，本发明提供了包括该电极的有机发光器件。

公开(公告)号：US20070105252A1

公开(公告)日：2007-05-10

申请号：US11589859

申请日：2006-10-31

申请人： Young Lee ,  Jae Lee ,  Jeoung Noh

发明人： Young Lee ,  Jae Lee ,  Jeoung Noh

IPC分类号： H01L21/00

CPC分类号： H01L51/56 ,  H01L51/003 ,  H01L51/5253 ,  H01L2227/326 ,  H01L2251/5338

摘要： The present invention relates to a method of manufacturing a device having a flexible substrate and a device having a flexible substrate manufactured using the method. According to the method of manufacturing a device having a flexible substrate of the invention, glass is used as a mother substrate, a polymer layer, which is used as a substrate, is formed on the mother substrate using a chemical vapor deposition method or a vacuum evaporation method, a device is formed, and finally, the substrate where the device is formed is separated from the mother substrate, such that a large-scale device having a flexible substrate can be manufactured. Further, as a substrate forming an organic light emitting device and a sealant are formed of the same material, the device is not bent due to stress generated from the device itself after the device is manufactured.

摘要翻译： 本发明涉及制造具有柔性基板的装置的方法和使用该方法制造的具有柔性基板的装置。 根据本发明的具有柔性基板的装置的制造方法，使用玻璃作为母基板，使用化学气相沉积法或真空法在母基板上形成用作基板的聚合物层 蒸发法，形成器件，最后将形成器件的衬底与母体衬底分离，从而可制造出具有柔性衬底的大型器件。 此外，由于形成有机发光器件和密封剂的基板由相同的材料形成，所以在器件制造之后，由于器件本身产生的应力，器件不会弯曲。

公开(公告)号：US20060070395A1

公开(公告)日：2006-04-06

申请号：US11143458

申请日：2005-06-03

申请人： Jae Lee ,  Jae Lee ,  June Min

发明人： Jae Lee ,  Jae Lee ,  June Min

IPC分类号： F25D17/04 ,  F25D17/06

CPC分类号： F25D17/045 ,  F25D17/062 ,  F25D2317/0665 ,  F25D2317/067 ,  F25D2500/02

摘要： A refrigerator capable of adjusting a discharge position and a quantity of cold air discharged into the refrigerator. The refrigerator includes an inner panel installed at a rear surface of a storage chamber and having cold air outlets for forming a cooling channel. The refrigerator also includes a variable duct installed at one of the cold air outlets such that the variable duct can move back and forth to vary a length of the cooling channel, and a plurality of cold air distribution holes formed in the variable duct.

摘要翻译： 一种能够调节排出位置的冰箱以及排入冰箱的冷气的量。 冰箱包括安装在存储室的后表面的内板，并具有用于形成冷却通道的冷气出口。 冰箱还包括安装在一个冷气出口处的可变管道，使得可变管道可前后移动以改变冷却通道的长度，以及形成在可变管道中的多个冷气分配孔。

公开(公告)号：US20080036055A1

公开(公告)日：2008-02-14

申请号：US11365246

申请日：2006-03-01

申请人： Jae Yee ,  Young Chung ,  Jae Lee ,  Terry Davis ,  Chung Han ,  Jae Ku ,  Jae Kwak ,  Sang Ryu

发明人： Jae Yee ,  Young Chung ,  Jae Lee ,  Terry Davis ,  Chung Han ,  Jae Ku ,  Jae Kwak ,  Sang Ryu

IPC分类号： H01L23/495 ,  H01L21/98

CPC分类号： H01L23/3107 ,  H01L23/4951 ,  H01L23/49541 ,  H01L23/49548 ,  H01L23/49551 ,  H01L24/32 ,  H01L24/48 ,  H01L24/73 ,  H01L2224/05599 ,  H01L2224/29007 ,  H01L2224/32014 ,  H01L2224/32245 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2224/73265 ,  H01L2224/85399 ,  H01L2924/00014 ,  H01L2924/01006 ,  H01L2924/01013 ,  H01L2924/01027 ,  H01L2924/01033 ,  H01L2924/01047 ,  H01L2924/0106 ,  H01L2924/01075 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/01082 ,  H01L2924/07802 ,  H01L2924/12042 ,  H01L2924/15311 ,  H01L2924/181 ,  H01L2924/00012 ,  H01L2924/3512 ,  H01L2924/00 ,  H01L2224/45015 ,  H01L2924/207 ,  H01L2224/45099

摘要： A lead frame for making a semiconductor package is disclosed. The leadframe's leads include a lead lock provided at a free end of each inner lead that is adapted to increase a bonding force of the inner lead to a resin encapsulate, thereby effectively preventing a separation of the inner lead from occurring in a singulation process involved in the fabrication of the semiconductor package. A semiconductor package fabricated using the lead frame and a fabrication method for the semiconductor package are also disclosed. The lead frame includes a paddle, a plurality of tie bars for supporting the corners of the paddle, a plurality of leads arranged at each of four sides or two facing sides of the paddle in such a fashion that they are spaced apart from an adjacent side of the paddle while extending perpendicularly to the associated side of the paddle, each of the leads having lead separation preventing means adapted to increase a bonding force of the lead to a resin encapsulate subsequently molded to encapsulate the lead frame for fabrication of the semiconductor package, and dam bars for supporting the leads and the tie bars. Additional package embodiments include exposed protrusions extending downward from the leads. The exposed protrusions are irradiated with a laser to remove set resin prior to a solder ball attachment step.

摘要翻译： 公开了一种用于制造半导体封装的引线框架。 引线框架的引线包括提供在每个内引线的自由端处的引线锁，其适于增加内引线与树脂封装件的结合力，从而有效地防止内引线的分离在所涉及的单个加工过程中发生 制造半导体封装。 还公开了使用引线框制造的半导体封装和用于半导体封装的制造方法。 引线框架包括桨，用于支撑桨的角的多个连杆，多个引线，其布置在桨的四个侧面或两个相对的侧面中，使得它们与相邻侧面间隔开 的叶片，同时垂直于桨叶的相关侧延伸，每个引线具有引线分离防止装置，其适于增加引线与随后模制的树脂封装件的结合力，以封装引线框架以制造半导体封装， 和用于支撑引线和连接条的阻挡条。 另外的封装实施例包括从引线向下延伸的暴露突起。 在焊球附着步骤之前，用激光照射暴露的突起以去除固化树脂。