Invention Application
- Patent Title: Thiazole compounds and methods of use
- Patent Title (中): 噻唑化合物和使用方法
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Application No.: US11652728Application Date: 2007-01-11
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Publication No.: US20070173506A1Publication Date: 2007-07-26
- Inventor: Qingping Zeng , John Allen , Matthew Bourbeau , Celia Dominguez , Christopher Fotsch , Nianhe Han , Fang-Tsao Hong , Xin Huang , Matthew Lee , Aiwen Li , Qingyian Liu , James Rider , Seifu Tadesse , Andrew Tasker , Vellarkad Viswanadhan , Xianghong Wang , Kurt Weiler , George Wohlhieter , Guomin Yao , Chester Yuan
- Applicant: Qingping Zeng , John Allen , Matthew Bourbeau , Celia Dominguez , Christopher Fotsch , Nianhe Han , Fang-Tsao Hong , Xin Huang , Matthew Lee , Aiwen Li , Qingyian Liu , James Rider , Seifu Tadesse , Andrew Tasker , Vellarkad Viswanadhan , Xianghong Wang , Kurt Weiler , George Wohlhieter , Guomin Yao , Chester Yuan
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Main IPC: A61K31/502
- IPC: A61K31/502 ; A61K31/4745 ; A61K31/4709 ; A61K31/427 ; C07D417/02

Abstract:
The invention relates to thiazole compounds of Formula I and Formula II and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such thiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.
Public/Granted literature
- US07514566B2 Thiazole compounds and methods of use Public/Granted day:2009-04-07
Information query
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